Endocrine Abstracts

Introduction: At the time of diagnosis of medullary thyroid carcinoma (MTC) 10 to 15% of patients have distant metastases, 25% of them develop them over a longer or shorter period of time. The usual metastases concern cervical lymphadenopathy, bone, lung and liver. There are also unusual secondary localisations. We report a case.Observation: A 56-year-old patient who consulted a year after apparition of cervical lymphadenopathy, whose fine needle aspirat...

Introduction: At the time of diagnosis of medullary thyroid carcinoma (MTC) 10 to 15% of patients have distant metastases, 25% of them develop them over a longer or shorter period of time. The usual metastases concern cervical lymphadenopathy, bone, lung and liver. There are also unusual secondary localisations. We report a case.Observation: A 56-year-old patient who consulted a year after apparition of cervical lymphadenopathy, whose fine needle aspirat...

Introduction: Disorders of sex development include a large number of congenital conditions related to unusual chromosomal sex (gonosomal abnormalities), defective testicular development, or abnormal hormone secretion or receptivity, resulting in unusual external and/or internal genitalia development rare. Patients and methods we report 3 cases of disorders of sex development 46XY reveled at adult age. clinical, biological and radiological funding are reported in the following ...

Introduction: Adrenal cavernous hemangioma is a rare tumor with few cases reported in the world. Usually this adrenal masses are incidentally discovered and non functional.Case report: We describe the case of a 63 year old male patient with a history of hypertension and treated prostate. He was referred to our endocrinology department with complaints of his left lower back. At the admission the BMI was 21 kg/m2, his blood pressure was 160/90 m...

Introduction: Adrenal myelolipoma is a rare, benign and nonfunctional tumor composed of mature adipose and hematopoietic cells. It is often of incidental finding (8%) and the diagnosis is based on radiological imaging. We report two cases of giant adrenal myelolipoma and discuss the diagnostic and therapeutic aspects of this pathology.Observation: Patient D.K 40 years old, hospitalized for adrenal mass revealed by right back pain radiating to the right h...

Background: Von Hippel–Lindau (VHL) is a rare, autosomal dominant syndrome characterized by the development of highly vascularized tumors in multiple organs. VHL affects approximately 1 in 35,000 live births. Tumors associated with VHL include hemangioblastom of the retina and central nervous system, pheochromocytomas, endolymphatic sac tumors of the middle ear, and epididymal or round ligament cysts. In 80% of patients, VHL disease is familial caused by mutations in the ...

Introduction: Proximal myopathy presents as symmetrical weakness of proximal upper and/or lower limbs. There is a broad range of underlying causes including drugs, alcohol, endocrine and metabolic myopathies such as primary hyperparathyroidism.Observation: We describe a 48-year-old male, hospitalised in neurology departement for exploration of severe proximal myopathy. Cliniquely, he presented progressive debilitating muscle weakness, severe muscle wasti...

Introduction: Prolactin-secreting tumors or prolactinomas comprise the most common pituitary tumor type, acconting of 47-66% of all pituitary tumors. These tumors can be treated with dopaminergic drugs (DA) however 10-15% of prolactinomas are DA resistant.Case 1: A 39 years old man followed for a geant agressif prolactinoma discovered following a progressive decline in visual acuity and associated with visual impairment (diplopia), the MRI of the sellar ...

Introduction: Pheochromocytomas and paragangliomas (PPGLs) are chromaffin cell tumors that arise from neuroectodermal cells. These tumors are characterized by a very heterogeneous natural history and an unpredictable ability to metastasize. The rate of metastatic disease ranges from lessthan 1% to 79%, depending on tumor site and size, age at diagnosis and genotype.30% are considered to be hereditary. Primary hyperparathyroidism can be associated with PPLGs. We report a case o...

Introduction: The Munchausen syndrome, also known as factitious disorder, involves a compulsion to simulate illness or trauma. Individuals may go as far as taking medication or inflicting harm on their bodies to evoke compassion. The aim of this report is to illustrate the example of factitious hypoglycemia, one of the most common forms of factitious disorders in the endocrine-metabolic field, accounting for 4-11% of all non-diabetic hypoglycemias.Observ...